PGT-M: Understanding Genetic Testing for Inherited Diseases in Fertility Treatments
Genetic testing plays a vital role in fertility treatments, particularly in cases where couples carry inherited genetic diseases. Preimplantation Genetic Testing for Monogenic/Single Gene Disorders, or PGT-M, is a powerful tool that helps identify and prevent the transmission of such genetic conditions. At Aspire Fertility Center in Bangalore, we offer the best fertility treatments that incorporate PGT-M to ensure successful outcomes for our patients.
What is PGT-M?
PGT-M is a specialized form of genetic testing performed during fertility treatments. It enables fertility specialists to screen embryos for specific inherited genetic diseases before they are transferred to the uterus. By identifying embryos without the genetic mutation, PGT-M significantly reduces the risk of passing on these conditions to future generations.
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Why is PGT-M necessary?
PGT-M is essential for couples who carry known genetic disorders or are at risk of passing on inherited diseases to their children. It offers invaluable insights into the genetic health of embryos, enabling fertility specialists to select and transfer only healthy embryos, thus increasing the chances of a successful pregnancy and the birth of a healthy child.
Consultation and Genetic Counseling
The PGT-M process begins with a consultation and genetic counseling session, where the couple’s medical and family history is thoroughly reviewed. The fertility specialist will discuss the genetic testing options and implications to help the couple make informed decisions.
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Ovarian Stimulation and Egg Retrieval
The female partner undergoes ovarian stimulation to produce multiple eggs. Once mature, the eggs are retrieved through a minimally invasive procedure under anesthesia.
In Vitro Fertilization (IVF)
The retrieved eggs are fertilized with the partner’s or donor’s sperm in the laboratory, creating embryos. The embryos develop in a controlled environment for a few days.
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Embryo Biopsy
At the appropriate stage of development, a small number of cells are gently removed from each embryo for genetic testing. This biopsy does not harm the embryo’s potential for successful implantation.
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Genetic Testing
The extracted cells from the embryos are analyzed using advanced genetic testing techniques. PGT-M focuses on specific genetic mutations or abnormalities, identifying embryos free of the targeted condition.
Embryo Selection and Transfer
Based on the genetic test results, the fertility specialist selects the genetically normal embryos for transfer to the uterus. The selected embryos are carefully placed into the uterus using a thin catheter, usually in a separate cycle.
Pregnancy Confirmation
A pregnancy test is conducted approximately two weeks after the embryo transfer to determine if pregnancy has been achieved.
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PGT-M is a crucial component of the best fertility treatments offered at Aspire Fertility Center in Bangalore. By identifying and transferring genetically normal embryos, PGT-M significantly increases the chances of successful pregnancies and healthy babies for couples at risk of passing on inherited genetic diseases. Our dedicated team of fertility specialists utilizes the latest techniques and technologies to provide personalized care and achieve the best outcomes for our patients.
Preimplantation Genetic Testing (PGT) offers different types, each with specific uses and benefits. Whether it’s PGT-A, PGT-SR, PGT-M, or Ni-PGT, these tests assist in selecting embryos with the desired genetic characteristics, increasing the chances of a successful pregnancy and fulfilling your family planning goals. Consult with our experienced fertility specialists at Aspire Fertility Centre to explore the different types of PGT and determine the most suitable option for your unique circumstances.
Remember, when it comes to fertility treatments, informed choices and expert guidance are paramount. Contact Aspire Fertility Center for the best fertility treatments in Bangalore and embark on your journey towards building a healthy and happy family.
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