A nonapoptotic sperm selection procedure, performed in the semen samples by using the MACS ART Annexin V Reagent. Indicated in patients with semen sample having High DFI.
The success of assisted-reproduction techniques (ART) depends largely on the quality of the gametes used in fertility treatment cycles. However, in most cases, seminal quality is still analyzed using only conventional seminal analysis. Due to its variability and low specificity, this is not particularly effective in diagnosing functional alterations or in characterizing the origin of sperm defects.
In order to address this issue, different sperm selection techniques have recently beendeveloped on the basis of different functional aspects and activation processes that happen during sperm-cell capacitation.
One such technique is the magnetic-activated cell-sorting (MACS) technique, which is used to identify and positively eliminate apoptotic cells from ejaculation the basis of the identification of externalized PS residues on apoptotic sperm cells by annexin V-conjugated super paramagnetic microbeads. This technique also reduces the proportion of sperm with fragmented DNA in the processed sample before using it for ART procedures.
The MACS sperm selection of human spermatozoa is a safe, easy, and suitable method for sperm preparations for ICSI use in a clinical setting.
Results presented in various studies conducted around the world indicated that the MACS selection technique may help to improve reproductive outcomes for autologous or oocyte-donation cycles in patients with high levels of sperm DNA fragmentation.
In addition, these studies observed no clinically adverse effects at the obstetric and perinatal levels in newborns who were closely monitored following sperm-selection treatments with MACS.
Studies show that it can increase the pregnancy rate by 10-15%. In the long run, this may also be lighter on the pocket as couples have a lower chance of requiring repeated cycles of IUI or IVF treatment.
Fertility Services Offered
In Vitro Fertilization (IVF)
IVF is a fertility treatment that involves fertilizing eggs with sperm in a laboratory setting. It is commonly used for various infertility issues, such as blocked fallopian tubes, low sperm count, or unexplained infertility.
Intrauterine Insemination (IUI)
IUI is a procedure in which washed and concentrated sperm are directly placed into the uterus during the woman’s ovulation period. It is often recommended for couples with mild male factor infertility, cervical factor infertility, or unexplained infertility.
Fertility Preservation (Egg Freezing, Sperm Freezing, Embryo Freezing)
Fertility preservation allows individuals or couples to preserve their reproductive cells (eggs, sperm, or embryos) for future use. It is commonly chosen by those who want to delay childbearing due to personal or medical reasons.
Preimplantation Genetic Testing (PGT)
PGT is a specialized genetic testing procedure performed on embryos before they are transferred to the uterus during an IVF cycle. It helps identify genetic disorders or chromosomal abnormalities in embryos, allowing for the selection of healthy embryos for transfer.
Laparoscopy and Hysteroscopy
These minimally invasive surgical procedures are used to diagnose and treat various reproductive conditions. Laparoscopy involves inserting a small camera through tiny incisions to examine the pelvic organs, while hysteroscopy involves inserting a thin tube with a camera through the cervix to visualize the inside of the uterus.
Ovulation Induction
Ovulation induction involves the use of medications to stimulate the ovaries to release eggs. It is commonly used in cases of hormonal imbalances or ovulation disorders to increase the chances of natural conception or enhance the success of assisted reproductive technologies.
High-Risk Pregnancy Care
Aspire Fertility Center provides comprehensive care for women with high-risk pregnancies, including close monitoring, specialized testing, and personalized treatment plans to ensure the health and well-being of both the mother and baby.
Counseling and Emotional Support
Alongside the medical services, Aspire Fertility Center offers counseling and emotional support to individuals and couples undergoing fertility treatments. These services provide guidance, coping strategies, and a supportive environment to address the emotional challenges that may arise during the fertility journey.
Note: The services offered may vary depending on the specific fertility center and the expertise of the fertility medical professionals. It is advisable to consult with Aspire Fertility Center directly for detailed information and personalized recommendations.
